“With ORLADEYO on a trajectory to more than double sales in its second year of launch after a very strong first year, we continue to demonstrate that what we are offering HAE patients is unique and fills their need for a therapy that offers both low burden of disease and low burden of treatment. We believe that our ability to successfully pursue challenging targets like plasma kallikrein is just the start, and we expect we will bring rare disease patients many more oral therapies to offer these patients the unique treatment options they are waiting for,” says Jon Stonehouse, President and CEO of BioCryst Pharmaceuticals, Inc., at the presentation of the financial results for the third quarter ended 30 September 2022.
ORLADEYO® (berotralstat) U.S. Launch
- The total number of patients on paid therapy grew by nine percent in the third quarter.
- New patient starts remained strong in the third quarter, in line with the running six quarter average.
- The ORLADEYO prescriber base grew by 11 percent in the third quarter.
These strong underlying growth trends were masked by accelerated direct shipments requested by patients late in the second quarter in June prior to the July 4 holiday weekend, plus a negative out of period reimbursement-related charge that was accounted for in the third quarter.
ORLADEYO® (berotralstat) Global Updates
In the third quarter, ORLADEYO was approved in Saudi Arabia. The company expects continued approvals and launches in additional countries.
“With the strong underlying growth fundamentals we continued to see from patients and physicians in the third quarter, and the further growth dynamics we expect to see in the fourth quarter, we are on track to more than double ORLADEYO revenue in 2022 compared to 2021,” says Charlie Gayer, Chief Commercial Officer of BioCryst.
(Source: BioCryst)
