Clinical Trials

According to clinicaltrials.gov under the U.S. National Institutes of Health, the EU Clinical Trials Register, and the International Clinical Trials Registry Platform under World Health Organization (WHO) the following trials should be recruiting at this moment (updated start of April 2024).

Read more about these and other clinical trials at:

www.clinicaltrials.gov
www.clinicaltrialsregister.eu
https://trialsearch.who.int/

A Study to Assess the Long-Term Safety and Efficacy of Donidalorsen in the Prophylactic Treatment of Hereditary Angioedema (HAE)

Belgium
Bulgaria
Canada
France
Germany
Israel
Italy
Netherlands
Poland
Puerto Rico
Spain
Turkey
United Kingdom
United States

https://clinicaltrials.gov/study/NCT05392114

A Study With Lanadelumab in Persons With Hereditary Angioedema (HAE) in Poland

Poland

https://clinicaltrials.gov/study/NCT05147181

A Gene Therapy Study of BMN 331 in Subjects With Hereditary Angioedema

Spain
United States

https://clinicaltrials.gov/study/NCT05121376

A Study of Lanadelumab in Teenagers and Adults With Hereditary Angioedema (HAE)

United Kingdom

https://clinicaltrials.gov/study/NCT05469789

A Study in Adults With Hereditary Angioedema (HAE) Who Currently Receive Icatibant at Home

United Kingdom

https://clinicaltrials.gov/study/NCT05489640

A Survey of Lanadelumab in Participants With Hereditary Angioedema

Japan

https://clinicaltrials.gov/study/NCT05397431

A Survey of Icatibant in Pediatric Participants With Hereditary Angioedema

Japan

https://clinicaltrials.gov/study/NCT05509569

A Study of STAR-0215 in Participants With Hereditary Angioedema

Canada
United States

https://clinicaltrials.gov/study/NCT05695248


PK Subtrial in Adolescent Patients With HAE Type I or II Participating in the KVD900-302 Trial

Australia
Austria
Bulgaria
France
Germany
Greece
Israel
Japan
Netherlands
New Zealand
Spain
United Kingdom
United States

https://clinicaltrials.gov/study/NCT05511922

CSL312_3003 Safety and Pharmacokinetic Study in Subjects 2 to 11 Years of Age With Hereditary Angioedema

Israel
United States

https://clinicaltrials.gov/study/NCT05819775

A Study to Review the Treatment and Outcomes of Teenagers and Adults With Non-histaminergic Angioedema With Normal C1 Inhibitor in Canada

Canada

https://clinicaltrials.gov/study/NCT05578417

Firazyr Patient Registry (Icatibant Outcome Survey – IOS)

Australia
Austria
Brazil
Czechia
Denmark
France
Germany
Greece
Israel
Italy
Spain
Sweden
United Kingdom

https://clinicaltrials.gov/study/NCT01034969

An Open-label Extension Trial to Evaluate the Long-term Safety of KVD900 for On-Demand Treatment of Angioedema Attacks in Adolescent and Adult Patients With Hereditary Angioedema (HAE)

Australia
Austria
Bulgaria
France
Germany
Greece
Hungary
Israel
Italy
Japan
Netherlands
New Zealand
North Macedonia
Poland
Portugal
Slovakia
South Africa
Spain
United Kingdom
United States

https://clinicaltrials.gov/study/NCT05505916

Extension Study of Oral PHA-022121 for Acute Treatment of Angioedema Attacks in Patients With Hereditary Angioedema

Bulgaria
Canada
Czechia
France
Germany
Hungary
Israel
Poland
Spain
United States

https://clinicaltrials.gov/study/NCT05396105

Status of Dental Care Practices in Patients With Hereditary Angioedema

France

https://clinicaltrials.gov/study/NCT05776784

Safety, Tolerability, PK, PD of ADX-324 in Healthy Volunteers and Hereditary Angioedema Patients

Australia

https://clinicaltrials.gov/study/NCT05691361

Identification and Characterization of Genetic Variants in Hereditary Angioedema

Spain

https://clinicaltrials.gov/study/NCT05833620

C1 Inhibitor Registry in the Treatment of Hereditary Angioedema (HAE) Attacks

Bulgaria, Croatia

https://www.clinicaltrials.gov/study/NCT01397864

A Study of Lanadelumab (Takhzyro) and Icatibant (Firazyr) in Persons with HAE in China

China

https://www.clinicaltrials.gov/study/NCT06346899

Study of Oral Deucrictibant Soft Capsule for On-Demand Treatment of Angioedema Attacks in Adolescents and Adults with Hereditary Angioedema (RAPIDe-3)

United States

https://www.clinicaltrials.gov/study/NCT06343779

Long-Term Follow-Up (LTFU) of Subjects Treated With NTLA 2002

France
New Zealand
United Kingdom

https://www.clinicaltrials.gov/study/NCT06262399

Angioedema Biomarker Research Study

United States

https://www.clinicaltrials.gov/study/NCT06210698