HAEi News

In its annual R&D briefing to investors CSL Limited demonstrates how the company is advancing a novel research portfolio across four strategic scientific platforms (Plasma Fractionation, Recombinant Technology, Cell and Gene Therapy, Adjuvanted Cell and Egg-based Vaccines) across six therapeutic areas (Immunology, Hematology, Respiratory, Cardiovascular and Metabolic, Transplant, Influenza Vaccines) and two businesses (CSL Behring [...]

The Journal of Allergy and Clinical Immunology (JACI) publishes data from the first 24 weeks of the APeX-2 trial of oral, once-daily berotralstat in patients with HAE. APeX-2 was a Phase 3, double-blind, placebo-controlled, parallel-group trial that evaluated the efficacy and safety of oral, once-daily berotralstat versus placebo over 24-weeks in 121 HAE patients ages 12 [...]

IONIS-PKK-LRx from Ionis Pharmaceuticals, Inc. is being evaluated in an investigator-initiated Phase 2 clinical study to determine its effectiveness in reducing the severity of respiratory complications in patients with COVID-19. The trial coordinators are Fernando G. Zampieri, M.D., Ph.D., and Alexandre Biasi Cavalcanti, M.D., Hospital do Coracao (HCor Research Institute), Sao Paulo, Brazil. The study [...]

KalVista Pharmaceuticals, Inc. provides an update on its franchise of oral therapies for treatment of HAE. “We have completed enrollment of our Phase 2 trial for our oral on-demand HAE treatment, KVD900, and remain on track to deliver data before the end of this year. We are also pleased to announce data from KVD824, our oral [...]

Ten months ago, HAE International and the non-profit organization of leading clinical and research facilities in the field of allergy and asthma GA2LEN established GA2LEN/HAEi Angioedema Centers of Reference and Excellence – or in short ACARE. “The joint venture with GA2LEN fulfills our longstanding goal of establishing a worldwide network of accredited angioedema care [...]

HAE International remains dedicated to finding innovative ways to serve the HAE community and are happy to announce the new initiative HAEi Advocacy Academy. “HAEi Advocacy Academy – a free online advocacy training platform that will be rolled out within the next few weeks – includes a variety of tutorials and other materials that [...]

Dr. José Egidio Fabiani, who distinguished himself within HAE in his native Argentina as well as in Latin America, passed away earlier this year. In a eulogy Alejandra Menendez, President of HAE Argentina, writes: “Dr. José Egidio Fabiani was the initial engine for the development of the study and treatment of HAE in Argentina. [...]

HAEi has developed HAE Companion an exciting new App that provides an easy way to access and store the popular HAE International emergency card that is currently a paper document. This App will become available on both Apple’s App Store and Google Play for the Android platform. “One of the key elements for the [...]

From Regional Patient Advocate Javier Santana Like many countries around the world, the Central American and Caribbean region has also been affected by the COVID-19 pandemic. This has allowed many governments to enact lockdown and establish new regulations to avoid contagion. We have not received information on HAE patients in the region who have [...]